ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2018, Vol. 49 ›› Issue (4): 746-753.doi: 10.11843/j.issn.0366-6964.2018.04.011

Previous Articles     Next Articles

Effects of Dietary Copper Levels on Copper Metabolism and Serum Biochemical Indices in Late Growing Male Mink

WU Xue-zhuang1,2, YANG Ying3, LIU Hui-tao3, GAO Xiu-hua2*, YANG Fu-he3, DAI Si-fa1, XING Xiu-mei3   

  1. 1. College of Animal Science, Anhui Science and Technology University, Bengbu 233100, China;
    2. Key Laboratory for Feed Biotechnology of the Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China;
    3. Institute of Special Animal and Plant Sciences of Chinese Academy of Agricultural Sciences, Changchun 130112, China
  • Received:2017-10-16 Online:2018-04-23 Published:2018-04-23

Abstract:

This experiment was conducted to study the effects of dietary copper levels on copper balance, serum trace element contents, serum lipid metabolism parameters and serum antioxidant indices in male mink. Eighty healthy (60±3) day-old male minks were randomly divided into 8 groups with 10 minks in each group. 0 (Control), 4 (Cu4), 8 (Cu8), 16 (Cu16), 32 (Cu32), 64 (Cu64), 128 (Cu128)and 256 mg·kg-1 (Cu256)of copper levels were added in basic diet, respectively. The pre-test period lasted for 7 days, and the trial lasted for 45 days. On day 30 of the trail, eight animals from each treatment group were selected randomly to determine copper balance. Blood samples were collected from mink before sacrifice to measure the serum biochemical indices. The results showed that:1) Intake of copper, fecal copper, urinary copper, retention copper had a linear and quadratic (P<0.01) increase with the increasing dietary copper level. 2) There was a linear and quadratic (P<0.01) effect of dietary copper level on plasma Cu concentrations. 3) Serum TC (linear, quadratic, P<0.01), TG (linear, P<0.05;quadratic, P<0.01) contents were decreased with the increasing dietary copper level. 4)There was a quadratic (P<0.01) effect of dietary copper level on plasma ceruloplasmin concentration and Cu-Zn superoxide dismutase activity. These results indicate that supplementing Cu in the diet can increase Cu retention and plasma Cu concentrations, but reduce serum TC and TG levels, and improve antioxidant enzyme activity.

CLC Number: